Where to get pizza in Port St. Lucie: 30 places, A to Z

Last checked Oct. 11, 2026. Refreshed every three months.

Port St. Lucie has pizza in every part of the city, but the biggest clusters are along Port St. Lucie Boulevard, Gatlin Boulevard, St. Lucie West Boulevard and SW Bayshore Boulevard. Many are New York-style shops; five are national chains.

How we made this list. We started from OpenStreetMap records inside Port St. Lucie’s city limits, the same data behind our local directory, and added places from the Florida Division of Hotels and Restaurants’ food license and inspection files, checking every address against the city boundary. We checked each place’s own website on Oct. 11, 2026. Many small pizzerias here have no website of their own, only third-party ordering pages; we kept those only where the state has a current license and an inspection on file, and we say so. We left out a Blaze Pizza and two Pizza Hut addresses that the chains’ own store lists no longer show, and a pizzeria on U.S. 1 we could not place inside the city limits. The list is alphabetical. It is not a ranking or a recommendation, and nobody paid to be on it. Run one of these places? Write to us to correct your entry.

The list

The places

Ah-Beetz New Haven Pizza is a New Haven-style pizzeria in St. Lucie West. Its site blocked our check; the state inspected it in August 2026.

Alfonso’s Pizza and Pasta, SW Brigantine Place. No website of its own; state inspection April 2026.

All American Pizzeria, SW Port St. Lucie Boulevard. No website of its own; state inspection March 2026.

Anthony’s Pizza calls itself a family cafe and pizzeria and says it picks its ingredients with care.

Antonio’s Pizza in the north end makes pizza, calzones and breadsticks for dine-in, takeout and delivery, and its older site says it delivers beer.

Big Apple Pizza has two shops, on SW Bayshore Boulevard and St. Lucie West Boulevard. No website of its own; both hold current state licenses.

Bobby’s Pizza, NW Selvitz Road. Its old web address now belongs to an unrelated site; state inspection September 2026.

Cam’s Pizzeria is the Port St. Lucie location of a New York pizzeria group with shops in Camillus, Oswego and other upstate towns.

D’Angelo’s Pizza and Subs, SW Bayshore Boulevard. No website of its own; state inspection September 2026.

Domino’s has five delivery and carryout stores in the city.

Estella’s Pizzaria, SW California Avenue. No website of its own; state inspection May 2026.

Francesca’s Pizza is a pizzeria on Port St. Lucie Boulevard with its menu on its site; it is closed Tuesday.

Goodfella’s Pizza has two shops, on Port St. Lucie Boulevard and NW California Boulevard. No website of its own; both were inspected by the state this year.

Labby’s Pizzeria sells 18-inch pies and slice specials from 11 a.m. to 3 p.m., dine-in or takeout only.

LaMattina’s Trattoria Pizza & Bar, in the Torino area. No website of its own; state inspection August 2026.

Little Caesars has three carryout stores in the city; its store finder would not load for us, and all three hold current state licenses.

Mama’s Pizzeria on U.S. 1 says its family’s pizza roots go back more than 30 years to the Bronx, and it takes reservation requests and delivery orders.

Marco’s Pizza on Gatlin Boulevard serves specialty and build-your-own pizzas for takeout and delivery.

Massimo’s Pizza & Pasta, Port St. Lucie Boulevard. Its site blocked our check; state inspection August 2026.

Mozzarella’s Pizzeria on SW Tulip Boulevard makes pizza, subs, wings and zeppole, with cauliflower crust as an option, for pickup and delivery.

Papa Johns has three delivery and carryout stores in the city. The SW Discovery Way store lists delivery from 10 a.m. to 12:30 a.m. Monday to Thursday and to 1:30 a.m. Friday and Saturday.

Pizza Hut has one restaurant on Gatlin Boulevard.

Pizza Vita, SE Floresta Drive. No website of its own; state inspection September 2026.

Pulcinella Pizzeria and Italian Market, in Tradition. No website of its own; state inspection September 2026.

Roma Pizzeria, SE Morningside Boulevard. No website of its own; state inspection October 2026.

Ruffino’s Italian Restaurant was founded in 1992, its site says, and serves New York-style pizza, including a white clam pie, alongside pasta and seafood. Dinner only, closed Monday.

Sal’s Italian Ristorante, St. Lucie West. No website of its own; state inspection August 2026.

St. Lucie West Pizzeria, Courtyard Circle. No website of its own; state inspection August 2026.

Times Square Pizza, SW Crosstown Parkway. No website of its own; state inspection February 2026.

Two Fat Guys From Brooklyn, Gatlin Boulevard. No website of its own; state inspection August 2026.

Related lists: wings, Mexican and Tex-Mex, breakfast and coffee, burgers, sushi and Asian, ice cream and desserts, bakeries, patios and outdoor dining and every list by category. Also: brunch, date night, the business directory and restaurant inspection scores.

Frequently asked questions

Where can I get pizza in Port St. Lucie?

Thirty pizza places operate inside the city limits, with the biggest groups on Port St. Lucie Boulevard, Gatlin Boulevard, St. Lucie West Boulevard and SW Bayshore Boulevard. The list is alphabetical, from Ah-Beetz to Two Fat Guys From Brooklyn.

Which Port St. Lucie pizza places are open late?

Marco’s Pizza on Gatlin Boulevard lists midnight closing Friday and Saturday and 11 p.m. other nights, and Pizza Hut on Gatlin Boulevard lists the same. Papa Johns on SW Discovery Way lists delivery to 12:30 a.m. most nights.

Which Port St. Lucie pizzerias are open on Monday?

Ruffino’s is closed Monday and Francesca’s opens at 4 p.m. Monday. Anthony’s, Labby’s, Cam’s and Mozzarella’s list Monday hours on their sites.

Is there pizza in Tradition?

Yes. Pulcinella Pizzeria and Italian Market is at 11510 SW Village Parkway, Times Square Pizza at 10676 SW Crosstown Parkway and Papa Johns at 10340 SW Discovery Way.